Endocrine Abstracts

Introduction: Gonadotroph adenomas usually present as clinically non-functioning sellar masses. They are extremely infrequent in children. Only some case report of children and adolescents with clinical manifestations of high serum gonadotrophin levels have been published. As in adult patients most of the gonadotroph adenomas have a silent growth, and therefore a late presentation as macroadenoma with mass effects.Case report: This 16-year-old girl prese...

Introduction: Postoperative diabetes insipidus (DI) remains a common complication after pituitary surgery. AVP measurement might contribute to a straightforward diagnosis, though, its measurement is cumbersome. Copeptin, the stable C-terminal glycopeptide of the AVP prohormone, is a reliable surrogate of AVP.We aimed to elucidate whether copeptin is a helpful marker in the diagnostic approach of postoperative DI.Methods/design: Pro...